GPC2-CAR T cells tuned for low antigen density mediate potent
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Descrição
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
BiCisCAR T cells targeting both GPC2 and CD276 show potent NB
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors. - Abstract - Europe PMC
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PDF) Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma
Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma - ScienceDirect
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
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Mechanisms of Resistance and Treatment of Relapse after CAR T-cell Therapy for Large B-cell Lymphoma and Multiple Myeloma - Transplantation and Cellular Therapy, Official Publication of the American Society for Transplantation and
